Targeted Sequencing and Resequencing Market by Technology (Sequencing and Re-sequencing), Application (Clinical application, Plant & Animal Sciences, Drug Development, and Others), End-use (Hospitals & Clinics, Academic Research, and Others), Type (DNA-based Targeted Sequencing and RNA-based Targeted Sequencing), and Region (North America, Europe, Asia-Pacific, and LAMEA): Opportunity Analysis and Industry Forecast, 2023-2032

Targeted Sequencing and Resequencing Overview

Targeted sequencing and resequencing is a technique for sequencing a sample's partial genome or specific sections of interest. It is an essential technique in genomics. Targeted sequencing needs a DNA preparation pre-sequencing stage called Target Enrichment in which target DNA sequences are either amplified or captured, and then afterward sequenced using DNA sequencers. These techniques have found widespread applications in medical research & personalized medicine and agriculture. In medical research they aid in understanding the genetic causes of diseases and potentially leading to improved diagnostics and treatments.

Global Targeted Sequencing and Resequencing Market Analysis

The global targeted sequencing and resequencing market size was $5.2 billion in 2022 and is predicted to grow with a CAGR of 22.4%, by generating a revenue of $39.1 billion by 2032.

COVID-19 Impact on Global Targeted Sequencing and Resequencing Market

The disruptions caused by the COVID-19 pandemic, including laboratory shutdowns, supply chain challenges, and reduced research funding, led to delays and adjustments in projects. Despite these obstacles, the market for targeted sequencing and resequencing market remained resilient. Research initiatives related to COVID-19 drove demand for sequencing technologies to track virus mutations and understand its spread. This spotlight on sequencing also highlighted the importance of rapid and accurate methods, spurring innovation in the field. However, broader research unrelated to the pandemic faced setbacks due to resource reallocation and limitations in conducting experiments. The market landscape saw a mixed impact. Companies offering sequencing services for COVID-19 research experienced a surge in demand, while others encountered delays in product development and customer orders.

Continuous Technological Developments in Genome Sequencers to Drive the Market Growth

The development of high-throughput sequencing platforms and next-generation sequencing (NGS) technologies has revolutionized the field of genomics. Target sequencing and resequencing offer numerous benefits in genetic research. This technique allows scientists to focus on specific regions of interest within a genome, enhancing the efficiency of analysis. This targeted approach reduces unnecessary data generation and saves both time and resources.  Besides, the growing understanding of the role of genetics in various diseases, such as cancer, inherited disorders, and rare diseases, has fuelled the demand for targeted sequencing and resequencing. Furthermore, these techniques contribute to personalized medicine. By focusing on genes associated with particular diseases or drug responses, clinicians can tailor treatments based on individual genetic profiles, leading to more effective and targeted therapies. Their ability to zoom in on specific genetic regions, detect rare variants, support comparative genomics, and advance personalized medicine makes them indispensable tools in the realm of genetics.

High Initial Cost to Restrain the Market Growth

Target sequencing and resequencing can be costly endeavors due to the need for specialized equipment and skilled personnel. This can make them less accessible to smaller research institutions or organizations with limited budgets. Moreover, the process is time-consuming and often takes weeks or even months to complete which can hinder timely decision-making or research progress. Additionally, errors can creep in during the sequencing process, leading to inaccuracies in the obtained data. Such inaccuracies might result from technical issues, sample contamination, or other factors, compromising the reliability of the findings.

Advancements in Target sequencing and Resequencing to Drive Excellent Opportunities

Targeted sequencing enables precise identification of genetic variations associated with diseases, leading to personalized treatments and drug development. Resequencing aids in developing crops with enhanced traits, improving yield, resilience, and nutrition. These techniques can help track biodiversity, aiding conservation efforts and understanding ecosystems. Target resequencing assists in identifying human remains, tracing ancestry, and solving criminal cases. Understanding microbial communities through sequencing offers insights into health, ecology, and disease prevention.  Advancements in genome sequencer contribute to encryption methods for secure data transmission. Target sequencing enables personalized wellness plans and ancestry tracing for individuals. Sequencing assists in identifying potential drug targets and evaluating drug efficacy.

Global Targeted Sequencing and Resequencing Market Share, by Technology, 2022

The sequencing sub-segment accounted for the highest market share in 2022. This technology enables scientists to focus on specific regions of interest in DNA, allowing them to zoom in on relevant genetic information.  The aim of target sequencing is to study particular genes or genomic regions, avoiding unnecessary data generation. This focused approach expedites analysis and conserves resources. The dominance of sequencing sub-segment is attributed to its versatility and adaptability in various research areas like medical diagnostics, agriculture, and evolutionary studies. The preference for sequencing is driven by its capacity to provide high-resolution insights into genetic makeup. It uncovers valuable information with improved accuracy, avoiding the limitations of older methods. Sequencing has revolutionized biological research by enabling a comprehensive understanding of DNA at the molecular level. Its focused and precise approach has propelled it to the forefront of genetic analysis, making it an indispensable tool for scientists across disciplines.

Global Targeted Sequencing and Resequencing Market Share, by Application, 2022

The clinical application sub-segment accounted for the highest market share in 2022. The focus on identifying specific genes or regions in a patient's DNA helps diagnose diseases and predict treatment responses. By pinpointing mutations causing disorders like cancer, clinicians tailor personalized therapies, improving patient outcomes. This precision minimizes side effects, enhancing the efficacy of interventions. Additionally, clinical settings demand accurate results, necessitating advanced techniques like target sequencing and resequencing. Identifying variations in genetic sequences aids in understanding genetic predispositions to diseases, facilitating early detection and prevention. These applications aid in genetic counselling, family planning, and disease management.

 Global Targeted Sequencing and Resequencing Market Share, by Type, 2022

The DNA-based targeted sequencing sub-segment accounted for the highest market share in 2022. Compared to older methods, DNA-based target sequencing offers high specificity, allowing researchers to zoom in on the exact regions of interest. This specificity reduces background noise and increases the chances of detecting relevant genetic variations. Additionally, advancements in DNA sequencing technologies have made the process faster, more cost-effective, and accessible, making it feasible for a wider range of projects. Researchers appreciate its adaptability across diverse research goals. Whether investigating rare genetic mutations related to diseases or studying genetic variations in populations, DNA-based target sequencing provides the needed precision. Its ability to focus on specific genetic regions rather than sequencing an entire genome further optimizes resource utilization.

Global Targeted Sequencing and Resequencing Market Share, by End-use, 2022

The academic research sub-segment accounted for the highest market share in 2022. Academic research stands out as the primary beneficiary of targeted sequencing and resequencing techniques due to their precise and efficient nature. These methods enable scientists to focus on specific genetic regions of interest, offering valuable insights into various biological processes. By pinpointing and comparing genetic variations, researchers can better understand the relationships between genes and traits, aiding advancements in fields like medicine, agriculture, and ecology. Such approaches aid researchers in deciphering genetic mutations responsible for diseases, leading to improved diagnostics and potential treatments.  The ease of customization and affordability of these techniques make them particularly attractive to academic settings with limited resources, promoting broader accessibility to cutting-edge research tools.

Global Targeted Sequencing and Resequencing Market Share, by Region, 2022

The North America targeted sequencing and resequencing market generated the largest revenue in 2022. The region boasts a robust ecosystem of research institutions, biotechnology companies, and academic centers that actively collaborate to advance genomics research. This collaborative atmosphere fosters the exchange of ideas and resources which facilitates the development and adoption of innovative sequencing technologies. Furthermore, the North America region offers a conducive environment for fostering innovation, with a strong emphasis on research funding, infrastructure, and technological advancements. This enables scientists and researchers to access cutting-edge equipment and stay at the forefront of genomics research. The presence of skilled professionals and experts in genomics also contributes to the dominance of North America region.  

Competitive Scenario in the Global Targeted Sequencing and Resequencing Market

Agreement and investing are the common strategies followed by the major market players. Some of the top leading targeted sequencing and resequencing market players are Agilent Technologies, Illumina, Inc, F. Hoffmann-La Roche Ltd, Thermo Fisher Scientific, Inc, DNASTAR Inc, PacBio, Bio-Rad Laboratories, Inc, Integrated DNA Technologies, Inc, Perkin Elmer, Inc., and RainDance Technologies, Inc.

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