Vitamin K Market Size, Share, Competitive Landscape and Trend Analysis Report by Type, Application, Route of Administration, Distribution Channel, and Region: Global Opportunity Analysis and Industry Forecast, 2024-2033

The vitamin K market was valued at $889.34 million in 2023 and is estimated to reach $2,086.09 million by 2033, exhibiting a CAGR of 8.9% from 2024 to 2033.

Market Introduction and Definition

Vitamin K is a fat-soluble vitamin that plays a key role in blood clotting (coagulation) and bone metabolism. There are two primary forms of vitamin K: vitamin K1 (phylloquinone), which is derived from plants, particularly leafy green vegetables, and vitamin K2 (menaquinone), which is synthesized by bacteria in the gut and also found in certain animal-based and fermented foods. In addition to its role in blood clotting, vitamin K is also important for bone health. It helps regulate calcium levels in bones and may be involved in the synthesis of bone proteins. The main function of vitamin K is its involvement in the production of proteins necessary for blood clotting. Specifically, it activates certain proteins that help to form blood clots and prevent excessive bleeding when injury occurs.

Key Takeaways

• The vitamin K market study covers 20 countries. The research includes a segment analysis of each country in terms of value ($million) for the projected period from 2024 to 2033.
• More than 1,500 product literatures, industry releases, annual reports, and other such documents of major energy storage system industry participants along with authentic industry journals, trade associations' releases, and government websites have been reviewed for generating high-value industry insights.
• The study integrates high-quality data, professional opinions and analysis, and critical independent perspectives. The research approach intends to provide a balanced view of global markets and assist stakeholders in making informed decisions in order to achieve their most ambitious growth objectives.

Industry Trends

• On August 16, 2022, Amphastar Pharmaceuticals, Inc. (NASDAQ:AMPH) announced that the U.S. Food and Drug Administration (FDA) approved the company's New Drug Application (NDA) for Epinephrine injection USP, 1 mg/10mL (0.1 mg/mL) Single Dose Pre-Filled Syringe.
• On December 5, 2022, BASF Pharma Solutions announced that the U.S. Food and Drug Administration (FDA) Center for Drug Evaluation and Research (CDER), Office of New Drugs, has accepted their excipient, Soluplus, into the FDA’s Pilot Program for the Review of Innovation and Modernization of Excipients (PRIME). This program aims to reduce the risks and burdens for pharmaceutical companies that wish to use novel excipients in addressing modern drug development challenges. It also provides a pathway for excipient manufacturers, such as BASF, to obtain FDA review of their novel excipients prior to their inclusion in an FDA-approved drug.
• In May 2021, Lesaffre bolstered its presence in the human nutrition and health market by acquiring NattoPharma, a renowned expert in Vitamin K2. This acquisition enhanced Lesaffre's research and marketing endeavors in the vitamin K segment, expanding its product portfolio and reinforcing its industry position.
• In February 2021, Kappa Bioscience unveiled intentions to expand its presence in the U.S., seeking to access fresh markets and grow its customer reach. This expansion initiative involves bolstering production of nutraceuticals through upgraded operational facilities, thus meeting rising demand and solidifying Kappa Bioscience's position in the U.S. market.

Key Market Dynamics

There has been an increase in awareness among consumers about the importance of vitamin K for various health benefits like bone health, cardiovascular support, and blood coagulation in the recent years. As people seek to proactively manage their health, they are more inclined to incorporate vitamin K into their diets or supplement routines. Moreover, with an aging population globally, there is an increased focus on preventive healthcare and nutritional support. Vitamin K's role in bone health becomes particularly significant as individuals age and become more susceptible to conditions like osteoporosis.

One of the primary concerns is the misconception that vitamin K supplementation leads to increased blood clotting. However, vitamin K2 (menaquinone) has a different role, particularly in bone health and arterial health, and is not associated with increased blood clotting. The confusion between different forms of vitamin K can lead to reluctance in using vitamin K supplements.

Vitamin K plays a vital role in bone metabolism and can contribute to maintaining healthy bones and cartilage. This aspect is crucial for joint support, especially in athletes prone to joint stress and impact injuries. Vitamin K is involved in the production of certain proteins essential for bone and joint health, including osteocalcin, which regulates bone mineralization, and matrix Gla protein (MGP), which helps maintain cartilage. Athletes require strong bones to withstand the demands of training and competition. Vitamin K contributes to bone density and strength, potentially reducing the risk of stress fractures and other bone injuries.

Parent Market Overview

The vitamin market is a diverse and expansive sector encompassing various vitamins, supplements, and related products aimed at promoting health and wellness. Vitamins such as A, D, E, and K, are stored in the body's fat tissues and liver. Vitamin C and the B-complex vitamins (e.g., B1, B2, B3, B6, B12, folate), are not stored in the body and need regular replenishment. Vitamin products are distributed through pharmacies, supermarkets, online platforms, and specialized health stores. In February 2023, Bayer AG unveiled the extension of its ‘Nutrient Gap Initiative’ to enhance nutritional access. The initiative targets reaching 50 million people in underserved communities by 2030, by expanding availability of essential vitamins and minerals. The program highlights nutritional supplementation as a key strategy to combat malnutrition in these populations.

Market Segmentation

The vitamin K Market is segmented into type, application, route of administration, distribution channel, and region. On the basis of type, the market is divided into vitamin K1 and vitamin K2. As per application, the market is segregated into prothrombin deficiency, Vitamin K Deficiency Bleeding (VKDB), dermal applications, and other applications. On the basis of route of administration, the market is classified into oral, parenteral, and topical. On the basis of distribution channel, the market is divided into offline and online. Region wise, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.

Country Market Outlook

The aging population in the U.S. is more prone to conditions like osteoporosis and cardiovascular issues, where vitamin K plays a critical role. This demographic trend is likely to lead to an increase in the demand for vitamin K supplements and fortified foods. Consumers are increasingly seeking preventive healthcare measures, driving the demand for nutritional supplements like vitamin K. The Council for Responsible Nutrition reported that 77% of adults in the U.S. consume dietary supplements. Also, chronic diseases such as cardiovascular diseases and osteoporosis are prevalent in the U.S. Vitamin K plays a role in cardiovascular health and bone metabolism, which presents an opportunity for regional market growth. According to the American Heart Association, cardiovascular diseases account for more than 840,000 deaths in the U.S. each year.

• On July 27, 2024, Octapharma USA announced that Balfaxar received FDA approval for rapidly reversing acquired coagulation factor deficiency due to vitamin K antagonist therapy in adult patients needing urgent surgery or invasive procedures. Balfaxar helps restore blood clotting by replenishing deficient clotting factors caused by warfarin therapy.
• The FDA approval is supported by the clinical trial LEX-209 (ClinicalTrials.gov Identifier: NCT02740335), which compared the efficacy and safety of Balfaxar head-to-head with a control 4F-PCC (Kcentra). The Phase III, randomized, double-blind, multicenter study was performed at 24 sites in the U.S. and Europe and randomized 208 patients to Balfaxar (N=105) or control 4F-PCC (N=103).

Competitive Landscape

The major players operating in the vitamin K market include NattoPharma ASA, BASF SE, Country Life, LLC (Kikkoman Corporation), Pfizer Inc., Amphastar Pharmaceuticals Inc., DSM, Kappa Bioscience, Livealth Biopharma Pvt. Ltd., NOW Foods, and Solgar Inc.

Recent Key Strategies and Developments

• In October 2023, Smidge Small Batch Supplements introduced grass-fed Australian Emu Oil as a source of real food vitamin K2. This addition expands their premium, clean product line to include a small-batch supplement delivering essential nutrients that may be missing even from the healthiest whole foods diet.
• According to the Bone Health and Osteoporosis Foundation's 2023 report, nearly 10 million Americans have osteoporosis, and an additional 44 million have low bone density, putting them at greater risk of fractures. This means that 54 million Americans aged 50 and older are at higher risk of bone fractures and should prioritize bone health. Statistics show that 1 in 2 women and up to 1 in 4 men will experience a bone fracture due to osteoporosis during their lifetime.

Key Sources Referred

1. Centers for Disease Control and Prevention (CDC)
2. National Institutes of Health (NIH)
3. U.S. Department of Agriculture (USDA)
4. Food and Drug Administration (FDA)
5. European Food Safety Authority (EFSA)

Key Benefits for Stakeholders

• This report provides a quantitative analysis of the vitamin K market segments, current trends, estimations, and dynamics of the vitamin K market analysis from 2023 to 2033 to identify the prevailing vitamin K market opportunities.
• The market research is offered along with information related to key drivers, restraints, and opportunities.
• Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
• In-depth analysis of the vitamin K market segmentation assists to determine the prevailing market opportunities.
• Major countries in each region are mapped according to their revenue contribution to the global vitamin K market statistics.
• Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.

Apart from the above mentioned points, the report includes the analysis of the regional as well as global vitamin K market trends, key players, market segments, application areas, and market growth strategies.

1. Research Methodology

1.1. Desk Research
1.2. Real time insights and validation
1.3. Forecast model
1.4. Assumptions and forecast parameters
1.5. Market size estimation

1.5.1. Top-down approach
1.5.2. Bottom-up approach

2. Report Scope

2.1. Market definition
2.2. Key objectives of the study
2.3. Market segmentation

3. Executive Summary
4. Market Overview

4.1. Introduction
4.2. Growth impact forces

4.2.1. Drivers
4.2.2. Restraints
4.2.3. Opportunities

4.3. Market value chain analysis

4.3.1. List of raw material suppliers
4.3.2. List of manufacturers 
4.3.3. List of distributors

4.4. Innovation & sustainability matrices

4.4.1. Technology matrix
4.4.2. Regulatory matrix

4.5. Porter’s five forces analysis

4.5.1. Bargaining power of suppliers
4.5.2. Bargaining power of consumers
4.5.3. Threat of substitutes
4.5.4. Threat of new entrants
4.5.5. Competitive Rivalry Intensity

4.6. PESTLE analysis

4.6.1. Political
4.6.2. Economical
4.6.3. Social
4.6.4. Technological
4.6.5. Legal
4.6.6. Environmental

4.7. Impact of COVID-19 on Vitamin K Market 

4.7.1. Pre-covid market scenario
4.7.2. Post-covid market scenario

5. Vitamin K Market  Analysis, by Type

5.1. Overview
5.2. vitamin K1

5.2.1. Definition, key trends, growth factors, and opportunities
5.2.2. Market size analysis, by region, 2022-2032
5.2.3. Market share analysis, by country, 2022-2032

5.3. Vitamin K2

5.3.1. Definition, key trends, growth factors, and opportunities
5.3.2. Market size analysis, by region, 2022-2032
5.3.3. Market share analysis, by country, 2022-2032

5.4. Research Dive Exclusive Insights

5.4.1. Market attractiveness
5.4.2. Competition heatmap

6. Vitamin K Market  Analysis, by Application

6.1. Overview
6.2. Prothrombin Deficiency

6.2.1. Definition, key trends, growth factors, and opportunities
6.2.2. Market size analysis, by region, 2022-2032
6.2.3. Market share analysis, by country, 2022-2032

6.3. Vitamin K Deficiency Bleeding (VKDB)

6.3.1. Definition, key trends, growth factors, and opportunities
6.3.2. Market size analysis, by region, 2022-2032
6.3.3. Market share analysis, by country, 2022-2032

6.4. Dermal Applications

6.4.1. Definition, key trends, growth factors, and opportunities
6.4.2. Market size analysis, by region, 2022-2032
6.4.3. Market share analysis, by country, 2022-2032

6.5. Other

6.5.1. Definition, key trends, growth factors, and opportunities
6.5.2. Market size analysis, by region, 2022-2032
6.5.3. Market share analysis, by country, 2022-2032

6.6. Research Dive Exclusive Insights

6.6.1. Market attractiveness
6.6.2. Competition heatmap

7. Vitamin K Market  Analysis, by Route Of Administration

7.1. Overview
7.2. Oral

7.2.1. Definition, key trends, growth factors, and opportunities
7.2.2. Market size analysis, by region, 2022-2032
7.2.3. Market share analysis, by country, 2022-2032

7.3. Parenteral

7.3.1. Definition, key trends, growth factors, and opportunities
7.3.2. Market size analysis, by region, 2022-2032
7.3.3. Market share analysis, by country, 2022-2032

7.4. Topical

7.4.1. Definition, key trends, growth factors, and opportunities
7.4.2. Market size analysis, by region, 2022-2032
7.4.3. Market share analysis, by country, 2022-2032

7.5. Research Dive Exclusive Insights

7.5.1. Market attractiveness
7.5.2. Competition heatmap

8. Vitamin K Market  Analysis, by Distribution Channel

8.1. Overview
8.2. Offline

8.2.1. Definition, key trends, growth factors, and opportunities
8.2.2. Market size analysis, by region, 2022-2032
8.2.3. Market share analysis, by country, 2022-2032

8.3. Online

8.3.1. Definition, key trends, growth factors, and opportunities
8.3.2. Market size analysis, by region, 2022-2032
8.3.3. Market share analysis, by country, 2022-2032

8.4. Research Dive Exclusive Insights

8.4.1. Market attractiveness
8.4.2. Competition heatmap

9. Vitamin K Market , by Region

9.1. North America

9.1.1. U.S.

9.1.1.1. Market size analysis, by Type, 2022-2032
9.1.1.2. Market size analysis, by Application, 2022-2032
9.1.1.3. Market size analysis, by Route of Administration, 2022-2032
9.1.1.4. Market size analysis, by Distribution Channel, 2022-2032

9.1.2. Canada

9.1.2.1. Market size analysis, by Type, 2022-2032
9.1.2.2. Market size analysis, by Application, 2022-2032
9.1.2.3. Market size analysis, by Route of Administration, 2022-2032
9.1.2.4. Market size analysis, by Distribution Channel, 2022-2032

9.1.3. Mexico

9.1.3.1. Market size analysis, by Type, 2022-2032
9.1.3.2. Market size analysis, by Application, 2022-2032
9.1.3.3. Market size analysis, by Route of Administration, 2022-2032
9.1.3.4. Market size analysis, by Distribution Channel, 2022-2032

9.1.4. Research Dive Exclusive Insights

9.1.4.1. Market attractiveness
9.1.4.2. Competition heatmap

9.2. Europe

9.2.1. Germany 

9.2.1.1. Market size analysis, by Type, 2022-2032
9.2.1.2. Market size analysis, by Application, 2022-2032
9.2.1.3. Market size analysis, by Route of Administration, 2022-2032
9.2.1.4. Market size analysis, by Distribution Channel, 2022-2032

9.2.2. UK

9.2.2.1. Market size analysis, by Type, 2022-2032
9.2.2.2. Market size analysis, by Application, 2022-2032
9.2.2.3. Market size analysis, by Route of Administration, 2022-2032
9.2.2.4. Market size analysis, by Distribution Channel, 2022-2032

9.2.3. France

9.2.3.1. Market size analysis, by Type, 2022-2032
9.2.3.2. Market size analysis, by Application, 2022-2032
9.2.3.3. Market size analysis, by Route of Administration, 2022-2032
9.2.3.4. Market size analysis, by Distribution Channel, 2022-2032

9.2.4. Spain

9.2.4.1. Market size analysis, by Type, 2022-2032
9.2.4.2. Market size analysis, by Application, 2022-2032
9.2.4.3. Market size analysis, by Route of Administration, 2022-2032
9.2.4.4. Market size analysis, by Distribution Channel, 2022-2032

9.2.5. Italy

9.2.5.1. Market size analysis, by Type, 2022-2032
9.2.5.2. Market size analysis, by Application, 2022-2032
9.2.5.3. Market size analysis, by Route of Administration, 2022-2032
9.2.5.4. Market size analysis, by Distribution Channel, 2022-2032

9.2.6. Rest of Europe

9.2.6.1. Market size analysis, by Type, 2022-2032
9.2.6.2. Market size analysis, by Application, 2022-2032
9.2.6.3. Market size analysis, by Route of Administration, 2022-2032
9.2.6.4. Market size analysis, by Distribution Channel, 2022-2032

9.2.7. Research Dive Exclusive Insights

9.2.7.1. Market attractiveness
9.2.7.2. Competition heatmap

9.3. Asia-Pacific

9.3.1. China

9.3.1.1. Market size analysis, by Type, 2022-2032
9.3.1.2. Market size analysis, by Application, 2022-2032
9.3.1.3. Market size analysis, by Route of Administration, 2022-2032
9.3.1.4. Market size analysis, by Distribution Channel, 2022-2032

9.3.2. Japan 

9.3.2.1. Market size analysis, by Type, 2022-2032
9.3.2.2. Market size analysis, by Application, 2022-2032
9.3.2.3. Market size analysis, by Route of Administration, 2022-2032
9.3.2.4. Market size analysis, by Distribution Channel, 2022-2032

9.3.3. India

9.3.3.1. Market size analysis, by Type, 2022-2032
9.3.3.2. Market size analysis, by Application, 2022-2032
9.3.3.3. Market size analysis, by Route of Administration, 2022-2032
9.3.3.4. Market size analysis, by Distribution Channel, 2022-2032

9.3.4. Australia

9.3.4.1. Market size analysis, by Type, 2022-2032
9.3.4.2. Market size analysis, by Application, 2022-2032
9.3.4.3. Market size analysis, by Route of Administration, 2022-2032
9.3.4.4. Market size analysis, by Distribution Channel, 2022-2032

9.3.5. South Korea

9.3.5.1. Market size analysis, by Type, 2022-2032
9.3.5.2. Market size analysis, by Application, 2022-2032
9.3.5.3. Market size analysis, by Route of Administration, 2022-2032
9.3.5.4. Market size analysis, by Distribution Channel, 2022-2032

9.3.6. Rest of Asia-Pacific

9.3.6.1. Market size analysis, by Type, 2022-2032
9.3.6.2. Market size analysis, by Application, 2022-2032
9.3.6.3. Market size analysis, by Route of Administration, 2022-2032
9.3.6.4. Market size analysis, by Distribution Channel, 2022-2032

9.3.7. Research Dive Exclusive Insights

9.3.7.1. Market attractiveness
9.3.7.2. Competition heatmap

9.4. LAMEA

9.4.1. Brazil

9.4.1.1. Market size analysis, by Type, 2022-2032
9.4.1.2. Market size analysis, by Application, 2022-2032
9.4.1.3. Market size analysis, by Route of Administration, 2022-2032
9.4.1.4. Market size analysis, by Distribution Channel, 2022-2032

9.4.2. UAE

9.4.2.1. Market size analysis, by Type, 2022-2032
9.4.2.2. Market size analysis, by Application, 2022-2032
9.4.2.3. Market size analysis, by Route of Administration, 2022-2032
9.4.2.4. Market size analysis, by Distribution Channel, 2022-2032

9.4.3. Saudi Arabia

9.4.3.1. Market size analysis, by Type, 2022-2032
9.4.3.2. Market size analysis, by Application, 2022-2032
9.4.3.3. Market size analysis, by Route of Administration, 2022-2032
9.4.3.4. Market size analysis, by Distribution Channel, 2022-2032

9.4.4. South Africa

9.4.4.1. Market size analysis, by Type, 2022-2032
9.4.4.2. Market size analysis, by Application, 2022-2032
9.4.4.3. Market size analysis, by Route of Administration, 2022-2032
9.4.4.4. Market size analysis, by Distribution Channel, 2022-2032

9.4.5. Rest of LAMEA

9.4.5.1. Market size analysis, by Type, 2022-2032
9.4.5.2. Market size analysis, by Application, 2022-2032
9.4.5.3. Market size analysis, by Route of Administration, 2022-2032
9.4.5.4. Market size analysis, by Distribution Channel, 2022-2032

9.4.6. Research Dive Exclusive Insights

9.4.6.1. Market attractiveness
9.4.6.2. Competition heatmap

10. Competitive Landscape

10.1. Top winning strategies, 2022

10.1.1. By strategy
10.1.2. By year

10.2. Strategic overview
10.3. Market share analysis, 2022

11. Company Profiles

11.1. NattoPharma ASA

11.1.1. Overview
11.1.2. Business segments
11.1.3. Product portfolio
11.1.4. Financial performance
11.1.5. Recent developments
11.1.6. SWOT analysis

11.2. BASF SE

11.2.1. Overview
11.2.2. Business segments
11.2.3. Product portfolio
11.2.4. Financial performance
11.2.5. Recent developments
11.2.6. SWOT analysis

11.3. Country Life,LLC (Kikkoman Corporation)

11.3.1. Overview
11.3.2. Business segments
11.3.3. Product portfolio
11.3.4. Financial performance
11.3.5. Recent developments
11.3.6. SWOT analysis

11.4. Pfizer Inc.

11.4.1. Overview
11.4.2. Business segments
11.4.3. Product portfolio
11.4.4. Financial performance
11.4.5. Recent developments
11.4.6. SWOT analysis

11.5. Amphastar Pharmaceuticals Inc.

11.5.1. Overview
11.5.2. Business segments
11.5.3. Product portfolio
11.5.4. Financial performance
11.5.5. Recent developments
11.5.6. SWOT analysis

11.6. DSM

11.6.1. Overview
11.6.2. Business segments
11.6.3. Product portfolio
11.6.4. Financial performance
11.6.5. Recent developments
11.6.6. SWOT analysis

11.7. Kappa Bioscience

11.7.1. Overview
11.7.2. Business segments
11.7.3. Product portfolio
11.7.4. Financial performance
11.7.5. Recent developments
11.7.6. SWOT analysis

11.8. Livealth Biopharma Pvt. Ltd.

11.8.1. Overview
11.8.2. Business segments
11.8.3. Product portfolio
11.8.4. Financial performance
11.8.5. Recent developments
11.8.6. SWOT analysis

11.9. NOW Foods

11.9.1. Overview
11.9.2. Business segments
11.9.3. Product portfolio
11.9.4. Financial performance
11.9.5. Recent developments
11.9.6. SWOT analysis

11.10. Solgar Inc

11.10.1. Overview
11.10.2. Business segments
11.10.3. Product portfolio
11.10.4. Financial performance
11.10.5. Recent developments
11.10.6. SWOT analysis

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