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ATP Assay Market, by Product (Consumables & Accessories, Instruments), Application (Contamination Testing, Disease Testing, Drug Discovery & Development), End Use (Pharmaceutical & Biotechnology Companies, Food & Beverage Industry, Hospitals & Diagnostics Laboratories, Academic & Research Institutions): Global Opportunity Analysis and Industry Forecast, 2020-2027

Diagnostics and Biotech

LI20101982

Pages: 310

Sep 2024

The ATP assay market was valued at $316.5 million in 2023 and is estimated to reach $631.8 million by 2033, exhibiting a CAGR of 7.3% from 2024 to 2033.

Market Introduction

The ATP bioluminescence assay is a noninvasive method used to assess cell viability based on the presence or absence of adenosine triphosphate (ATP), the energy molecule within living cells. This assay relies on the enzymatic reaction between luciferase and luciferin, producing bioluminescence in the presence of ATP. Living cells generate a bioluminescent signal, while dead cells lack ATP and do not produce light. By measuring the intensity of bioluminescence, researchers can quantify the number of viable cells in a sample. This versatile assay finds applications across various fields, including sanitation evaluation, food processing, drug development, and oncology research.

Key Takeaways

  • The ATP assay market study covers 20 countries. The research includes a segment analysis of each country in terms of value ($million) for the projected period from 2024 to 2033.
  • More than 1,500 product literatures, industry releases, annual reports, and other such documents of major ATP assay industry participants along with authentic industry journals, trade associations' releases, and government websites have been reviewed for generating high-value industry insights.
  • The study integrates high-quality data, professional opinions and analysis, and critical independent perspectives. The research approach intends to provide a balanced view of global markets and assist stakeholders in making informed decisions in order to achieve their most ambitious growth objectives.

Industry Trends

  • In November 2023, a groundbreaking study conducted by Sartorius unveiled the revolutionary potential of the Incucyte® Live-Cell Analysis System in tumor research. Using 3D multi-spheroid assays, researchers explored the influence of stromal cells on tumor morphology and the efficacy of chemotherapeutic agents. Their findings, published recently, highlighted the system's capacity to provide real-time, automated insights into tumor dynamics, paving the way for more effective cancer therapies.
  • In June 2023, the research published in the journal Nature, has shed light on a critical mechanism underlying cancer progression: the role of ectopic ATP synthase (eATP synthase) in stimulating the secretion of extracellular vesicles from cancer cells. Under conditions of serum starvation, cancer cells express higher levels of eATP synthase, leading to increased production of extracellular vesicles. These extracellular vesicles, essential for communication within the tumor microenvironment, play a significant role in cancer progression. The study also uncovered that eATP synthase-generated extracellular ATP stimulates extracellular vesicle secretion by enhancing P2X7 receptor-triggered calcium influx. These findings highlight the potential of targeting eATP synthase as a therapeutic strategy against tumor development.

Key Market Dynamics

ATP assay has gained significant popularity in recent years as by correlating bioluminescence with bacterial viability, ATP assay offers a faster and less laborious approach to assess antibiotic efficacy. The standardization process, including determining background levels, detection limits, and linearity, ensures reliable and accurate results. The ability of ATP assays to categorize pharmacodynamic parameters, such as synergy and bactericidal effect, provides valuable insights into antibiotic efficacy.

However, ATP assay faces certain constraints as it is not sensitive enough for spore detection, potentially yielding false negatives due to low ATP levels in spores. Luminescence from food and interference from sanitizers and chemicals can further affect accuracy. Additionally, ATP assays are not replacements for traditional microbiological methods and require prompt testing.

The versatility of aptamer-based biosensors allows for the detection of ATP through various methods, including fluorescence and electrochemistry. As a result, these innovative platforms hold significant potential for precise and efficient detection of ATP, addressing critical needs in biomedical research, clinical diagnostics, and environmental monitoring. These factors are anticipated to generate excellent opportunities in the ATP assay market in the coming years.

Global ATP Assay Market: Patent Analysis

Year

Scientist Name

 

Organization Name

 

Country

Description

Sept 2023

 

Marcel Gubler

Annie Moisan

Adrian B. Roth

Hoffmann-La Roche Inc.

U.S.

IN VITRO NEPHROTOXICITY SCREENING ASSAY

The invention relates to methods for predicting the in vivo nephrotoxicity of a nucleic acid molecule, in particular a nucleic acid molecule such as a siRNA or an antisense oligonucleotide using an in vitro cell based assay measuring the levels of EGFR as toxicity biomarker, potentially in combination with other biomarkers like ATP and KIM-1.

May 2023

 

Joon Tae PARK

Yun Haeng LEE

Young Joo BYUN

Do Young CHOI

Inu Research & Business Foundation

Korea University Research and Business Foundation, Sejong Campus

U.S.

PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING AGING OR AGE-RELATED DISEASES

High-throughput screening (HTS) was performed regarding cell proliferation, one of symptoms of senescence. As a result, KB1541, which was the most effective on cell proliferation, was earned. The present invention described how the compound regulates cell proliferation and senescence. The present invention uncovered what proteins interacted with the compound using streptavidin-magnetic beads after treating with biotin-connected KB1541. Consequently, it was identified that mitochondrial proteins interacted with the compound. In ATP assay, electron microscope and IP assay, the inventors identified that the compound regulated mitochondrial proteins and thereby increased ATP production as well as recovered senescence.

April 2023

 

Julian IHSSEN

Urs SPITZ

Biosynth AG

U.S.

LUCIFERASE-BASED METHODS FOR DETECTING BACTERIAL AND FUNGAL CELLS AND ASSESSING SUSCEPTIBILITY OF BACTERIAL CELLS TO ANTIBIOTICS

The present invention relates to a method for assessing cell viability of bacterial and fungal cells and to a method for the detection of bacterial and fungal cells with specific enzyme activities. The methods of the present invention rely on the real-time measurement of the level of luminescence signal from a luciferase enzyme directly from a growing culture of bacterial or fungal cells. Furthermore, the present invention relates to a method for assessing susceptibility of bacterial cells to antibiotics by measuring ATP levels using a luciferase assay system.

August 2022

 

ISHIMARU MASAKO

NODA HIDEYUKI

Hitachi High-Tech Corp

 

Japan

TO PROVIDE A CELL DETECTION DEVICE THAT PERFORMS DETECTION OF BACTERIA IN A SAMPLE BY THE ATP ASSAY WITH HIGH SENSITIVITY, AND SHORTENS THE DETECTION TIME

A cell detection device that detects a cell in a sample comprises: a sealed container having a first container which houses a culture solution including the sample, a second container having a luminescence reagent which emits light by contact of the culture solution, and an adding mechanism which separates a part of the culture solution and adds it from the first container to the luminescence reagent of the second container; a photodetector which detects luminescence caused by addition of the culture solution to the luminescence reagent; and a calculation part which calculates a luminescence quantity from a detection signal of the photodetector and determines proliferation of the cells on the basis of changes over time of the luminescence quantity, where the adding mechanism intermittently repeats separating of a part of the culture solution to be added to the luminescence reagent.

Market Segmentation

The ATP assay market is segmented into product, application, end user, and region. On the basis of product, the market is divided into consumables and instruments. On the basis of application, the market is divided into contamination testing, disease testing, drug discovery & development. On the basis of end user, the market is divided into pharmaceutical & biotechnology, food & beverage, hospitals & diagnostics, and academic & research institutions. Region wise, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.

Country Market Outlook

The demand for ATP assays remains high in the U.S., owing to the presence of prominent ATP assay provider such as G-Biosciences! The ATP assays offered by this company has remarkable sensitivity, detecting ATP concentrations as low as 10-12 M, it's invaluable for enzyme assays, microbial contamination detection in various products, and assessing cell viability.

Additionally, its ease of use and rapid results make it attractive for high-throughput screening applications. In the U.S., industries like pharmaceuticals, food and beverage, healthcare, and environmental monitoring heavily rely on ATP assays for quality control, research, and regulatory compliance.

Leading providers of ATP assays in North America include Thermo Fisher Scientific, Promega Corporation, and Abcam. These companies offer a range of ATP detection kits catering to different research needs and applications. Their products are trusted for their reliability, sensitivity, and ease of use, making them preferred choices among researchers and industry professionals alike.

Competitive Landscape

The major players operating in the ATP assay market include Agilent Technologies, Inc., Danaher Corporation, Thermo Fisher Scientific, Inc., Merck KGaA, Abcam plc, 3M, PromoCell GmbH, Promega Corporation, Neogen Corporation, Geno Technology, Inc., and others.

Recent Key Strategies and Developments

  • In June 2023, LuminUltra introduced BugCount® Fuel, a groundbreaking microbial test for assessing fuel contamination swiftly and accurately. Leveraging their proven 2nd Generation ATP technology, the kit offers rapid results in just minutes, crucial for industries like aviation and marine facing fuel-related challenges. With increasing demand for microbial testing due to rising transport needs and green initiatives, BugCount® Fuel fills a vital gap, providing actionable insights to prevent performance issues and ensure operational efficiency.
  • In May 2023, a groundbreaking study led by researchers at Nagoya University, Japan, uncovered ATP's pivotal role in mammalian ovulation, potentially revolutionizing infertility treatments. The research reveals how ATP, acting as a neurotransmitter in the brain, stimulates kisspeptin neurons, triggering the release of luteinizing hormone (LH) crucial for ovulation. This discovery opens avenues for novel infertility treatments in humans and livestock, offering hope to individuals grappling with ovulation disorders. The findings, published in the Journal of Neuroscience, mark a significant leap forward in reproductive science.

Key Sources Referred

  1. Promega Corporation
  2. Thermo Fisher Scientific Inc.
  3. National Institutes of Health (NIH)
  4. Creative Bioarray
  5. Abcam Limited.

Key Benefits for Stakeholders

  • This report provides a quantitative analysis of the ATP assay market segments, current trends, estimations, and dynamics of the ATP assay market analysis from 2023 to 2033 to identify the prevailing ATP assay market opportunities.
  • The market research is offered along with information related to key drivers, restraints, and opportunities.
  • Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
  • In-depth analysis of the ATP assay market segmentation assists to determine the prevailing market opportunities.
  • Major countries in each region are mapped according to their revenue contribution to the global ATP assay market statistics.
  • Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
  • The report includes the analysis of the regional as well as global ATP assay market trends, key players, market segments, application areas, and market growth strategies.

In addition to providing a detailed analysis of key players in the global market, the report is valuable in highlighting business performance, operating segments, product portfolio, and strategic moves of market players to showcase the competitive scenario.

Aspect

Particulars

Historical Market Estimations

2021-2022

Base Year for Market Estimation

2023

Forecast Timeline for Market Projection

2024-2033

Geographical Scope

North America, Europe, Asia-Pacific, and LAMEA

Segmentation by Product
  • Consumables
  • Instruments

Segmentation by Application
  • Contamination Testing
  • Disease Testing
  • Drug Discovery & Development

Segmentation by End User
  • Pharmaceutical & Biotechnology
  • Food & Beverage
  • Hospitals & Diagnostics
  • Academic & Research Institutions

Key Companies Profiled
  • AbbVie Inc.
  • Cynosure Aesthetics
  • Solta Medical
  • Evolus Inc.
  • Lumenis Be Ltd.
  • Revance Galderma
  • Alma Lasers
  • Candela Corporation
  • Cutera, Inc.
  • Merz Pharma

    1. Research Methodology

    1.1. Desk Research
    1.2. Real time insights and validation
    1.3. Forecast model
    1.4. Assumptions and forecast parameters
    1.5. Market size estimation

    1.5.1. Top-down approach
    1.5.2. Bottom-up approach

    2. Report Scope

    2.1. Market Definition
    2.2. Key objectives of the study
    2.3. Market segmentation

    3. Executive Summary
    4. Market Overview

    4.1. Introduction
    4.2. Growth impact forces

    4.2.1. Drivers
    4.2.2. Restraints
    4.2.3. Opportunities

    4.3. Market value chain analysis

    4.3.1. List of suppliers
    4.3.2. List of manufacturers 
    4.3.3. List of distributors

    4.4. Innovation & sustainability matrices

    4.4.1. Technology matrix
    4.4.2. Regulatory matrix

    4.5. Porter’s five forces analysis

    4.5.1. Bargaining power of suppliers
    4.5.2. Bargaining power of consumers
    4.5.3. Threat of substitutes
    4.5.4. Threat of new entrants
    4.5.5. Competitive Rivalry Intensity

    4.6. PESTLE analysis

    4.6.1. Political
    4.6.2. Economical
    4.6.3. Social
    4.6.4. Technological
    4.6.5. Legal
    4.6.6. Environmental

    4.7. Impact of COVID-19 on the ATP Assay Market

    4.7.1. Pre-covid market scenario
    4.7.2. Post-covid market scenario

    5. ATP Assay Market Analysis, by Product

    5.1. Overview
    5.2. Consumables  

    5.2.1. Definition, key trends, growth factors, and opportunities
    5.2.2. Market size analysis, by region, 2023-2033
    5.2.3. Market share analysis, by country, 2023-2033

    5.3. Instruments

    5.3.1. Definition, key trends, growth factors, and opportunities
    5.3.2. Market size analysis, by region, 2023-2033
    5.3.3. Market share analysis, by country, 2023-2033

    5.4. Research Dive Exclusive Insights

    5.4.1. Market attractiveness
    5.4.2. Competition heatmap

    6. ATP Assay Market Analysis, by Application

    6.1. Overview
    6.2. Contamination Testing

    6.2.1. Definition, key trends, growth factors, and opportunities
    6.2.2. Market size analysis, by region, 2023-2033
    6.2.3. Market share analysis, by country, 2023-2033

    6.3. Disease Testing

    6.3.1. Definition, key trends, growth factors, and opportunities
    6.3.2. Market size analysis, by region, 2023-2033
    6.3.3. Market share analysis, by country, 2023-2033

    6.4. Drug Discovery & Development

    6.4.1. Definition, key trends, growth factors, and opportunities
    6.4.2. Market size analysis, by region, 2023-2033
    6.4.3. Market share analysis, by country, 2023-2033

    6.5. Research Dive Exclusive Insights

    6.5.1. Market attractiveness
    6.5.2. Competition heatmap

    7. ATP Assay Market Analysis, by End User

    7.1. Overview
    7.2. Pharmaceutical & Biotechnology

    7.2.1. Definition, key trends, growth factors, and opportunities
    7.2.2. Market size analysis, by region, 2023-2033
    7.2.3. Market share analysis, by country, 2023-2033

    7.3. Food & Beverage

    7.3.1. Definition, key trends, growth factors, and opportunities
    7.3.2. Market size analysis, by region, 2023-2033
    7.3.3. Market share analysis, by country, 2023-2033

    7.4. Hospitals & Diagnostics

    7.4.1. Definition, key trends, growth factors, and opportunities
    7.4.2. Market size analysis, by region, 2023-2033
    7.4.3. Market share analysis, by country, 2023-2033

    7.5. Academic & Research Institutions 

    7.5.1. Definition, key trends, growth factors, and opportunities
    7.5.2. Market size analysis, by region, 2023-2033
    7.5.3. Market share analysis, by country, 2023-2033

    7.6. Research Dive Exclusive Insights

    7.6.1. Market attractiveness
    7.6.2. Competition heatmap

    8. ATP Assay Market, by Region

    8.1. North America

    8.1.1. U.S.

    8.1.1.1. Market size analysis, by Product, 2023-2033
    8.1.1.2. Market size analysis, by Application, 2023-2033
    8.1.1.3. Market size analysis, by End User, 2023-2033

    8.1.2. Canada

    8.1.2.1. Market size analysis, by Product, 2023-2033
    8.1.2.2. Market size analysis, by Application, 2023-2033
    8.1.2.3. Market size analysis, by End User, 2023-2033

    8.1.3. Mexico

    8.1.3.1. Market size analysis, by Product, 2023-2033
    8.1.3.2. Market size analysis, by Application, 2023-2033
    8.1.3.3. Market size analysis, by End User, 2023-2033

    8.1.4. Research Dive Exclusive Insights

    8.1.4.1. Market attractiveness
    8.1.4.2. Competition heatmap

    8.2. Europe

    8.2.1. Germany 

    8.2.1.1. Market size analysis, by Product, 2023-2033
    8.2.1.2. Market size analysis, by Application, 2023-2033
    8.2.1.3. Market size analysis, by End User, 2023-2033

    8.2.2. UK

    8.2.2.1. Market size analysis, by Product, 2023-2033
    8.2.2.2. Market size analysis, by Application, 2023-2033
    8.2.2.3. Market size analysis, by End User, 2023-2033

    8.2.3. France

    8.2.3.1. Market size analysis, by Product, 2023-2033
    8.2.3.2. Market size analysis, by Application, 2023-2033
    8.2.3.3. Market size analysis, by End User, 2023-2033

    8.2.4. Spain

    8.2.4.1. Market size analysis, by Product, 2023-2033
    8.2.4.2. Market size analysis, by Application, 2023-2033
    8.2.4.3. Market size analysis, by End User, 2023-2033

    8.2.5. Italy

    8.2.5.1. Market size analysis, by Product, 2023-2033
    8.2.5.2. Market size analysis, by Application, 2023-2033
    8.2.5.3. Market size analysis, by End User, 2023-2033

    8.2.6. Rest of Europe

    8.2.6.1. Market size analysis, by Product, 2023-2033
    8.2.6.2. Market size analysis, by Application, 2023-2033
    8.2.6.3. Market size analysis, by End User, 2023-2033

    8.2.7. Research Dive Exclusive Insights

    8.2.7.1. Market attractiveness
    8.2.7.2. Competition heatmap

    8.3. Asia-Pacific

    8.3.1. China

    8.3.1.1. Market size analysis, by Product, 2023-2033
    8.3.1.2. Market size analysis, by Application, 2023-2033
    8.3.1.3. Market size analysis, by End User, 2023-2033

    8.3.2. Japan 

    8.3.2.1. Market size analysis, by Product, 2023-2033
    8.3.2.2. Market size analysis, by Application, 2023-2033
    8.3.2.3. Market size analysis, by End User, 2023-2033

    8.3.3. India

    8.3.3.1. Market size analysis, by Product, 2023-2033
    8.3.3.2. Market size analysis, by Application, 2023-2033
    8.3.3.3. Market size analysis, by End User, 2023-2033

    8.3.4. Australia

    8.3.4.1. Market size analysis, by Product, 2023-2033
    8.3.4.2. Market size analysis, by Application, 2023-2033
    8.3.4.3. Market size analysis, by End User, 2023-2033

    8.3.5. South Korea

    8.3.5.1. Market size analysis, by Product, 2023-2033
    8.3.5.2. Market size analysis, by Application, 2023-2033
    8.3.5.3. Market size analysis, by End User, 2023-2033

    8.3.6. Rest of Asia-Pacific

    8.3.6.1. Market size analysis, by Product, 2023-2033
    8.3.6.2. Market size analysis, by Application, 2023-2033
    8.3.6.3. Market size analysis, by End User, 2023-2033

    8.3.7. Research Dive Exclusive Insights

    8.3.7.1. Market attractiveness
    8.3.7.2. Competition heatmap

    8.4. LAMEA

    8.4.1. Brazil

    8.4.1.1. Market size analysis, by Product, 2023-2033
    8.4.1.2. Market size analysis, by Application, 2023-2033
    8.4.1.3. Market size analysis, by End User, 2023-2033

    8.4.2. UAE

    8.4.2.1. Market size analysis, by Product, 2023-2033
    8.4.2.2. Market size analysis, by Application, 2023-2033
    8.4.2.3. Market size analysis, by End User, 2023-2033

    8.4.3. Saudi Arabia

    8.4.3.1. Market size analysis, by Product, 2023-2033
    8.4.3.2. Market size analysis, by Application, 2023-2033
    8.4.3.3. Market size analysis, by End User, 2023-2033

    8.4.4. South Africa

    8.4.4.1. Market size analysis, by Product, 2023-2033
    8.4.4.2. Market size analysis, by Application, 2023-2033
    8.4.4.3. Market size analysis, by End User, 2023-2033

    8.4.5. Rest of LAMEA

    8.4.5.1. Market size analysis, by Product, 2023-2033
    8.4.5.2. Market size analysis, by Application, 2023-2033
    8.4.5.3. Market size analysis, by End User, 2023-2033

    8.4.6. Research Dive Exclusive Insights

    8.4.6.1. Market attractiveness
    8.4.6.2. Competition heatmap

    9. Competitive Landscape

    9.1. Top winning strategies, 2023

    9.1.1. By strategy
    9.1.2. By year

    9.2. Strategic overview
    9.3. Market share analysis, 2023

    10. Company Profiles

    10.1. Agilent Technologies, Inc.

    10.1.1. Overview
    10.1.2. Business segments
    10.1.3. Product portfolio
    10.1.4. Financial performance
    10.1.5. Recent developments
    10.1.6. SWOT analysis

    10.2. Danaher Corporation

    10.2.1. Overview
    10.2.2. Business segments
    10.2.3. Product portfolio
    10.2.4. Financial performance
    10.2.5. Recent developments
    10.2.6. SWOT analysis

    10.3. Thermo Fisher Scientific, Inc.

    10.3.1. Overview
    10.3.2. Business segments
    10.3.3. Product portfolio
    10.3.4. Financial performance
    10.3.5. Recent developments
    10.3.6. SWOT analysis

    10.4. Merck KGaA

    10.4.1. Overview
    10.4.2. Business segments
    10.4.3. Product portfolio
    10.4.4. Financial performance
    10.4.5. Recent developments
    10.4.6. SWOT analysis

    10.5. Abcam plc

    10.5.1. Overview
    10.5.2. Business segments
    10.5.3. Product portfolio
    10.5.4. Financial performance
    10.5.5. Recent developments
    10.5.6. SWOT analysis

    10.6. 3M

    10.6.1. Overview
    10.6.2. Business segments
    10.6.3. Product portfolio
    10.6.4. Financial performance
    10.6.5. Recent developments
    10.6.6. SWOT analysis

    10.7. PromoCell GmbH

    10.7.1. Overview
    10.7.2. Business segments
    10.7.3. Product portfolio
    10.7.4. Financial performance
    10.7.5. Recent developments
    10.7.6. SWOT analysis
    10.8. Promega Corporation

    10.8.1. Overview

    10.8.2. Business segments
    10.8.3. Product portfolio
    10.8.4. Financial performance
    10.8.5. Recent developments
    10.8.6. SWOT analysis

    10.9. Neogen Corporation

    10.9.1. Overview
    10.9.2. Business segments
    10.9.3. Product portfolio
    10.9.4. Financial performance
    10.9.5. Recent developments
    10.9.6. SWOT analysis

    10.10. Geno Technology, Inc.
    10.10.1. Overview
    10.10.2. Business segments
    10.10.3. Product portfolio
    10.10.4. Financial performance
    10.10.5. Recent developments
    10.10.6. SWOT analysis

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