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LI20101850 |
Pages: 280 |
Oct 2023 |
Cell Dissociation Overview
Cell dissociation is the process of separating tissues or cell aggregates into individual cells. This is an essential step in many biological and biomedical applications, including cell culture, cell isolation, flow cytometry, and other cellular assays. Obtaining a single-cell solution while keeping the vitality and functionality of the cells is the aim of cell dissociation. The first step in the procedure is getting the desired tissue or cell sample. This could be a solid tissue, a cell culture, or biological cell aggregates. To get the intended result, the dissociation process might need to be optimised. Variables including incubation duration, temperature, enzyme concentration, and mechanical force should be changed depending on the tissue or cell type.
Global Cell Dissociation Market Analysis
The global cell dissociation market size was $315.5 million in 2022 and is predicted to grow at a CAGR of 13.6%, by generating a revenue of $1,118.0 million by 2032.
COVID-19 Impact on Global Cell Dissociation Market
In order to comprehend the virus, its impact on the human body, and potential therapies or vaccines, biomedical research has increased dramatically as a result of COVID-19. Techniques for cell dissociation were essential in isolating and researching particular cell types pertinent to COVID-19 research.
In order to increase productivity and lower the risk of contamination, research facilities adopted automation and cutting-edge technology more quickly after the epidemic. With a probable shift towards automated dissociation techniques, this tendency also altered the growth of the cell dissociation market.
Rising Interest in Regenerative Medicine and Cell Therapy to Drive the Market Growth
In the process of finding new drugs and doing cell-based research, cell separation is a crucial stage. The need for cell dissociation products is growing as the pharmaceutical and biotechnology sectors continue to prioritise creating novel treatments and undertaking extensive cellular studies. In regenerative medicine and cell therapy applications, where the separation and manipulation of particular cell populations are vital, cell dissociation plays a crucial role. The demand for effective cell dissociation methods has increased due to the growing interest in regenerative medicine and cell-based therapeutics, which is predicted to boost the growth of the global cell dissociation market during the forecast period. The in vitro development of functional tissues or organ-like structures is a key component of both tissue engineering and organoid research. Dissociation products are required because cell dissociation is required to create these structures from primary tissues or stem cell cultures.
Cell Viability and Functionality Concerns to Restrain the Market Growth
The employment of enzymes and mechanical processes in cell dissociation procedures frequently raises ethical questions, especially when dealing with human tissues or stem cells. The development and commercialization of cell dissociation products may be more difficult and expensive due to legal and ethical limitations. Certain cell dissociation techniques may have an impact on cell viability and functioning, which could result in diminished cell performance in subsequent applications. The difficulty of sustaining cell viability and cellular functioning during the dissociation process can affect how usable dissociated cells are. All these factors may impede the market growth in the coming future.
Advancements in Cell Dissociation Methods to Drive Excellent Opportunities
As biotechnology and the life sciences continue to advance, more advanced and effective cell dissociation methods are anticipated to be developed. Enzyme, apparatus, and automation advancements will probably enhance dissociation procedures, making them more dependable, repeatable, and user-friendly. Tissue engineering, organoid research, and the creation and production of cell-based therapeutics will all greatly benefit from cell dissociation. All these factors are expected to create massive growth opportunities for the cell dissociation market during the forecast period.
Global Cell Dissociation Market Share, by Product, 2022
The enzymatic dissociation sub-segment accounted for the highest market share in 2022. When opposed to mechanical dissociation, enzymatic dissociation is a relatively quick and effective way to create single-cell suspensions. It is appropriate for applications needing large volumes of isolated cells since it enables researchers to produce a high yield of viable cells in a shorter amount of time. Numerous tissues and cell types can be separated using enzymes. This method is flexible and can be used in a variety of research and therapeutic contexts since different enzymes can be used depending on the tissue or cell source.
Global Cell Dissociation Market Share, by Type, 2022
The tissue dissociation sub-segment accounted for the highest market size in 2022. Tissue dissociation is necessary to isolate individual cells from intricate tissues and examine particular cell types and their roles. The development of our knowledge of many biological processes and disease mechanisms depends on this. A crucial stage in the development of cell-based therapeutics and regenerative medicine is tissue dissociation. It makes it possible to separate therapeutic cells, including stem cells, for use in tissue repair and transplantation. Tissue dissociation techniques and tools have improved in efficiency and repeatability, making the procedure more dependable and available to researchers. Tissue dissociation is essential for the creation of biobanks, where dissociated cells can be stored for upcoming research and therapeutic applications. Tissue dissociation techniques and tools have improved in efficiency and repeatability, making the procedure more dependable and available to researchers.
Global Cell Dissociation Market Share, by End-use, 2022
The pharmaceutical & biotechnology companies sub-segment accounted for the highest market size in 2022. Pharmaceutical companies use cell dissociation procedures for medication research and screening to obtain pure and viable cell populations. Cell separation enables researchers to examine how possible drug candidates affect particular cell types, assisting in the identification of interesting leads for further investigation. Companies in the biotechnology industry are actively working to produce regenerative medicine and cell-based therapeutics. Cell dissociation is a crucial stel to get therapeutic cells, like stem cells, for transplantation and tissue repair applications. Biobanks are created by pharmaceutical and biotechnology businesses to preserve significant cell lines and samples for upcoming research and development. Cell dissociation is necessary for the long-term storage and banking of cells. Pharmaceutical and biotechnology businesses are drawn to the ongoing developments in cell dissociation technologies because they are looking for effective and repeatable processes, such as automated systems and new enzyme formulations.
Global Cell Dissociation Market Share, by Region, 2022
The North America cell dissociation market accounted for the highest market share in 2022. This is mainly because the healthcare system in the North America region is highly developed and includes hospitals, research facilities, and biotechnology firms. The need for cell dissociation products for use in therapeutic, diagnostic, and research purposes in medicine is supported by this infrastructure. Cell dissociation products are extensively used in the biotechnology and pharmaceutical sectors of the region for projects involving drug discovery, bioprocessing, and personalised medicine.
Competitive Scenario in the Global Cell Dissociation Market
Product development and strategic partnerships are the common strategies adopted by the major players of the market. For instance, in 2021, Diamyd Medical chose Cytiva's FlexFactory technology for producing precision medicine type-1 diabetic vaccines as part of a partnership between Danaher (Cytiva) and Diamyd Medical.
Some of the leading cell dissociation market players are Merck KGaA, F. Hoffmann-La Roche Ltd., Thermo Fisher Scientific, HiMedia Laboratories, Danaher Corp., PAN-Biotech, STEMCELL Technologies, Sartorius AG, BD, and Miltenyi Biotec
| Aspect | Particulars |
| Historical Market Estimations | 2021 |
| Base Year for Market Estimation | 2022 |
| Forecast Timeline for Market Projection | 2023-2032 |
| Geographical Scope | North America, Europe, Asia-Pacific, and LAMEA |
| Segmentation by Product |
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| Segmentation by Type |
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| Segmentation by End-use |
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| Key Companies Profiled |
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