Immunoprecipitation Market Size, Share, Competitive Landscape, and Trend Analysis Report by Type, End User, and Region: Global Opportunity Analysis and Industry Forecast, 2024-2033

The immunoprecipitation market was valued at $901.00 million in 2023 and is estimated to reach $2,035.42 million by 2033, exhibiting a CAGR of 8.5% from 2024 to 2033.

Market Introduction and Definition

Immunoprecipitation is a technique used in molecular biology to isolate a specific protein or antigen from a mixture of proteins or other molecules. The process involves using an antibody that specifically binds to the target protein or antigen. The antibody is usually connected to a solid support, such as agarose beads or magnetic beads. When the antibody binds to its target protein, the protein-antibody complex can be precipitated out of solution using centrifugation or another separation method. This allows researchers to isolate and study the target protein or antigen, as well as any associated molecules, such as DNA or RNA. Immunoprecipitation is commonly used in various applications, including protein-protein interaction studies, chromatin immunoprecipitation (ChIP) assays, and co-immunoprecipitation experiments.

Key Takeaways

• The immunoprecipitation market study covers 20 countries. The research includes a segment analysis of each country in terms of value ($million) for the projected period from 2024 to 2033.
• More than 1,500 product literatures, industry releases, annual reports, and other such documents of major energy storage system industry participants along with authentic industry journals, trade associations' releases, and government websites have been reviewed for generating high-value industry insights.
• The study integrates high-quality data, professional opinions and analysis, and critical independent perspectives. The research approach intends to provide a balanced view of global markets and assist stakeholders in making informed decisions in order to achieve their most ambitious growth objectives.

Industry Trends

• In March 2022, The T2T Consortium released initial results from its work on fully assembling the human genome. Scientists provided a thorough and comprehensive description on the genome sequence, genetic variations, epigenetic markers, gene expression patterns, and other significant discoveries obtained from a comprehensive ‘telomere-to-telomere’ (T2T) representation of the human reference genome.
• In February 2022, MilliporeSigma, operating under its Sigma-Aldrich division, granted BetterSeeds, an Israeli agbio company, the rights to utilize its collection of CRISPR-related intellectual property specifically for plant applications.
• In February 2021, the National Institute of Allergy and Infectious Diseases (NIAID) began a Phase 1 clinical trial to assess the safety and immune response of an Epstein-Barr Virus (EBV) gp350-Ferritin Nanoparticle Vaccine. This study includes secondary endpoints to evaluate immunogenicity using the luciferase immunoprecipitation assay.
• In December 2020, in Bio-Protocol study titled 'Chromatin Immunoprecipitation (ChIP) to Assess Histone Marks in Auxin-treated Arabidopsis thaliana Inflorescence Tissue', researchers utilized chromatin immunoprecipitation, combined with quantitative PCR (ChIP-qPCR), to pinpoint DNA binding protein binding sites and detect histone modifications at specific locations on the genome.

Key Market Dynamics

Immunoprecipitation is crucial in identifying potential drug targets and understanding disease mechanisms, driving its adoption in the pharmaceutical industry. In the production of biopharmaceuticals, such as antibodies and recombinant proteins, immunoprecipitation is integral for quality control and validation. The technique ensures that the biologics produced meet the necessary standards for purity and functionality. Moreover, governments worldwide are increasingly supporting the biotechnology and pharmaceutical industries through funding and policy initiatives. For instance, in 2022, the U.S. government allocated over $40 billion for biomedical research through the National Institutes of Health (NIH). Furthermore, the European Union's Horizon Europe program allocated approximately $102.55billion for research and innovation from 2021 to 2027, with significant funding directed towards health and biotechnology sectors. These factors are predicted to drive the immunoprecipitation market growth during the forecast period.

The immunoprecipitation market growth is projected to be hampered primarily due to the high cost of equipment and reagents. Immunoprecipitation procedures demand specialized equipment, such as centrifuges, incubators, and magnetic separation devices, along with high-quality reagents like antibodies and protein A/G beads. In regions with emerging economies, the financial barrier posed by the high costs of immunoprecipitation equipment and reagents can significantly impede the growth of the market. Limited budgets may force institutions to prioritize other research methods or areas that require less financial investment, further restraining the immunoprecipitation market growth.

Advancements in immunoprecipitation techniques, such as chromatin immunoprecipitation (ChIP) and co-immunoprecipitation (Co-IP), are expanding the capabilities and efficiency of these methods, creating new opportunities for market growth. The National Institutes of Health (NIH) regularly funds research projects aimed at improving immunoprecipitation techniques. According to their data, funding for projects related to immunoprecipitation has increased by 15% over the last five years. This indicates a strong emphasis on technological advancements in the immunoprecipitation field. Moreover, the national science foundation (NSF) provides grants for research in various scientific fields, including biotechnology. Their reports show a significant uptick in grants awarded for projects focusing on improving immunoprecipitation methodologies. These factors are anticipated to create opportunities in the immunoprecipitation market during the forecast years as well.

Patent Analysis of Global Immunoprecipitation Market

The global immunoprecipitation market is experiencing significant growth, driven by innovative solutions and an increase in demand for effective therapies. Patent analysis in this market reveals key trends and insights:

In June 2022, in Korea, Institute of Ceramic Engineering and Technology, introduced the immunoprecipitation method using an antibody-binding protein and a calsequestrin fusion protein. The invention specifically pertains to the use of an antibody-binding protein and a calsequestrin fusion protein for immunoprecipitation; an immunoprecipitation kit utilizing the antibody-binding protein and calsequestrin fusion protein; and an immunoprecipitation method employing the antibody-binding protein and calsequestrin fusion protein.

Market Segmentation

The immunoprecipitation market is segmented into type, end user, and region. On the basis of type, the market is classified into individual protein immunoprecipitation, co-immunoprecipitation (Co-IP), chromatin immunoprecipitation (ChIP), RNA immunoprecipitation (RIP), and others. On the basis of end user, the market is divided into pharmaceutical & biotechnology industries, contract research organizations (CROs), and academic & research institutes. Region wise, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.

Regional Market Outlook

North America has been experiencing an increasing burden of chronic diseases such as cancer, autoimmune disorders, and neurological diseases. Immunoprecipitation techniques are crucial in research related to understanding the molecular mechanisms underlying these diseases, thus driving demand for related products and services. Moreover, regulations set by government agencies like the Food and Drug Administration (FDA) in the U.S. or Health Canada play a crucial role in shaping the market. Changes in regulations regarding research methodologies, quality standards, or approval processes are expected to impact the demand for immunoprecipitation technologies.

On March 29, 2023, Thermo Fisher Scientific, a global leader in scientific services, and Arsenal Biosciences, Inc. (ArsenalBio), a clinical-stage company specializing in advanced CAR-T cell therapies for solid tumors, announced an update regarding strategic collaboration to advance the development of manufacturing processes for new cancer treatments.

Competitive Landscape

The major players operating in the immunoprecipitation market include Air Liquide, Thermo Fisher Scientific Inc, Abcam Plc, BioLegend, Bio-Rad Laboratories, Biologics International Corp, Creative Proteomics, GenScript Biotech Corporation, Merck KGaA, Novus Biologicals, and others.

Recent Key Strategies and Developments

• In January 2022, BioNTech and Crescendo Biologics revealed a worldwide partnership to create precision immunotherapies, such as mRNA-based antibodies and engineered cell therapies, for cancer and other diseases. BioNTech will use Crescendo's Humabody VH platform to develop multi-specific immunotherapies targeting areas chosen by BioNTech.
• In 2019, Merck & Co. Inc. inaugurated a new life science center dedicated to R&D in the fields of oncology, immunology, and immuno-oncology.

Key Sources Referred

1. National Institutes of Health (NIH)
2. Centers for Disease Control and Prevention (CDC)
3. World Health Organization (WHO)
4. European Medicines Agency (EMA)
5. Food and Drug Administration (FDA)

Key Benefits for Stakeholders

• This report provides a quantitative analysis of the immunoprecipitation market segments, current trends, estimations, and dynamics of the immunoprecipitation market analysis from 2024 to 2033 to identify the prevailing immunoprecipitation market opportunities.
• The market research is offered along with information related to key drivers, restraints, and opportunities.
• Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
• In-depth analysis of the immunoprecipitation market segmentation assists to determine the prevailing market opportunities.
• Major countries in each region are mapped according to their revenue contribution to the global immunoprecipitation market statistics.
• Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.

Apart from the points mentioned above, the report includes the analysis of the regional as well as global immunoprecipitation market trends, key players, market segments, application areas, and market growth strategies.